The Longevity Docs Club⎮ Radical life extension⎮Physical Activity and Atherosclerosis
Your sneak peek into the world of Longevity Docs.
Hey Docs,
So many exciting news this week!
At Longevity Docs, we believe that by sharing knowledge and supporting one another, we can push the boundaries of what's possible in longevity medicine.
We’re all about the people, the community, and the collaboration. It’s about learning from each other, building together, and advancing our mission by lifting others up.
This week’s newsletter brings you exciting updates, new opportunities, and insights straight from our thriving community:
Community:
Longevity CEOs Lunch with Founders Forum
Introducing The Club
Members Spotlight: Dr. Jessica Shepherd and Dr. Darshan Shah
Buzz in the Chat:
how to optimize hormone therapy?
best way to boost NAD levels?
how space travel affect mitochondria?
is genetic testing worth it?
what’s the best recovery hack?
should we worry about GLP-1 agonists?
top post-surgery supplements?
does exercise type matter for arteries?
Publications:
Radical life extension is not pausible
Chronic inflammation and Post-COVID fatigue
Sex differences in muscle energetics and fatigue
Tramadol use and dementia risk
Physical activity an atherosclerosis prevention
Press:
Do people in Blue Zones actually live longer
Human Longevity May Have Reached its Upper Limit
Happy Sunday!
Dr. David Luu
🚨 Community
🍽️ Longevity Power Lunch
Hosted by Brent Hoberman (Founders Forum) and Dr. David Luu in the heart of Soho, NYC, the lunch brought together leading physicians, scientists, entrepreneurs, and investors for an intimate discussion on the current state and future of longevity science, medicine, and the evolving longevity economy.
Notable guests included Dr. Eric Verdin (Buck Institute), Dr. Frank Lipman, Dr. Jack Kreindler (Wellfounded), Piraye Beim (Celmatix), Jean Drouin (Clarify Health), Pr. Zahi Fayad (Mount Sinai), Ylan Boureau, Roy Bejarano (Scale Healthcare), Dr. Jaskaren Randhawa (Sama Oral Health), and Jacqueline Corbelli (Sustain Chain).
🔥 Introducing The Longevity Docs Club
We heard you! Following the oversubscribed Private Club experience at the Mastermind, we’re thrilled to announce the launch of the Longevity Docs Club. Think of a Soho House for longevity physicians. More access to top experts, cutting-edge knowledge, exclusive events and the support network you need to excel in longevity medicine. The Club is designed to help you grow your practice, build strong leadership, and stay ahead in longevity medicine.
As a member, you’ll get:
Community: Global physician directory and members-only digital channels.
Events: In-person exclusive events, VIP access, networking with industry leaders.
News & Insights: Briefings, podcasts, and expert articles to keep you ahead.
Learning: Watch exclusive masterclass, content, live & past events online.
Perks: Preferred access and discounts on innovations from our trusted partners.
Research: Collaborate on patient registries and clinical trials.
This is more than a membership; it’s your all-access pass to lead the future of longevity medicine.
Spots are limited to just 30.
Email us at meriem@longevitydocs.org to get on the list.
🌟 Spotlight
Congratulations to Jessica Shepherd on her new role as CMO at Hers! We're excited to see how she will drive innovation and excellence in women's health and longevity.
Kudos to Darshan Shah on the launch of his podcast, Extend! Wishing him success in spreading insights and knowledge on health and longevity.
💬 Buzz in the Chat
How to optimize hormone therapy?
Members shared insights on balancing DHEA supplementation, managing hormone-related conditions, and addressing risks of synthetic hormones. discussions also covered effective HRT protocols for menopause and the safe use of contraceptives.
Best way to boost NAD levels?
Members debated various NAD supplements like NMN, NR, and 1-MNA, emphasizing the importance of balancing NAD restoration with proper methylation support. Immune health boosters like colostrum and vitamin C were also highlighted.
How space travel affect mitochondria?
Conversations explored how reduced gravity and space environments might impact mitochondrial health, potentially affecting cellular integrity and metabolic adaptability.
Is genetic testing worth it?
Feedback was mixed on the cost and practicality of whole genome sequencing (WGS). While some see it as a valuable tool for personalized care, others noted the importance of pre-test counseling to manage patient anxiety.
What’s the best recovery hack?
Members shared their go-to recovery protocols, including the use of peptides like BPC157 and TB4, and Exercise With Oxygen Therapy (EWOT). Practical tips were provided on post-surgery care to optimize healing and reduce stiffness.
Should we worry about GLP-1 agonists?
Discussions addressed potential risks associated with synthetic GLP-1 receptor agonists, especially for long-term use in managing metabolic health and longevity.
Top post-surgery supplements?
Recommendations included using vitamin C, collagen peptides, and targeted peptides (BPC157, TB4) to speed up recovery. timing and dosage were highlighted as key factors for effective results.
Does exercise type matter for arteries?
Insights were shared on how different exercises (aerobic vs. resistance) affect arterial stiffness. The community emphasized the cardiovascular benefits of choosing the right workout routine based on individual health needs.
🩺 Publications
Implausibility of radical life extension in humans in the twenty-first century
The paper argues that radical life extension is unlikely due to biological constraints and limitations of current scientific advancements.
Nature Aging - Recommended by Dr. Giovanni Campanile
Chronic inflammation, neuroglial dysfunction, and plasmalogen deficiency as a new pathobiological hypothesis addressing the overlap between post-COVID-19 symptoms and myalgic encephalomyelitis/chronic fatigue syndrome
Proposes a new hypothesis linking chronic inflammation, neuroglial issues, and plasmalogen deficits to the shared pathology between post-COVID-19 symptoms and chronic fatigue syndrome.
Brain Research Bulletin- Recommended by Dr. Elizabeth Yurth
Sex differences in the association between skeletal muscle energetics and perceived physical fatigability: the Study of Muscle, Mobility and Aging (SOMMA)
Examines how muscle energetics differ between men and women, impacting perceived fatigue and aging-related mobility issues.
Geroscience - Recommended by Dr. Woody Merrel
Tramadol use and incident dementia in older adults with musculoskeletal pain: a population-based retrospective cohort study
This study found that exposure to tramadol was associated with an increased risk of dementia.
Nature Scientific Reports - Recommended by Dr. Woody Merrel
Preventive Effects of Physical Activity on the Development of Atherosclerosis: A Narrative Review
This review provides insights into effective exercise strategies for reducing cardiometabolic risk and emphasizes the importance of personalized approaches in exercise interventions.
J Atheroscler Thromb - Recommended by Dr. Giovanni Campanile
🌐 In the News
Do people in Blue Zones actually live longer
Human Longevity May Have Reached its Upper Limit
🗓️ Events & conferences
Biomarkers of Aging Conference - November 1-2, Boston, MA
A4M Fest - December 13-15, Las Vegas
Founders Longevity Forum - Singapore, February 27-28, 2025
The Longevity Med Summit - Lisbon, May 6-8, 2025
Cannes Longevity Festival: Cannes, France - June 24-26, 2025
About Longevity Docs Mastermind
The Longevity Docs Mastermind is a physician-only event focused on precision and evidence-based longevity medicine. This is where the medical leaders of today shape the future of longevity.
New York City - October 5-6, 2024
Convene 101 Park Avenue, NYC