The Business of Longevity Is Here • Should We Test Teens? • Dr. Eric Verdin Joins the Summit
Issue 44: The front page of longevity medicine - curated by doctors, for doctors.
Hey Docs,
Hello from Martinique - my wife Moana’s home. We met here years ago, when I was a cardiothoracic surgery resident on the island. Returning always reminds me what true luxury really is: nature, ocean, music, great food, deep rest, and laughing with the people you love.
As we move fast (building practices, scaling ideas, creating impact) I’ve been reflecting on this: We pursue longevity, yes. But what’s the point of more time, if not to live moments like these?
Biological homeostasis is essential. But so is life homeostasis.
So today, I just want to say thank you. For showing up. For building this field with courage and curiosity. For believing that medicine can be more than treating disease.
In this week’s newsletter:
Cover Story – Should We Be Testing Teens for Longevity?
A thoughtful dive into labs, limits, and the future of prevention.Inside Longevity Docs: Speaker Spotlight Dr. Eric Verdin Joins Cannes Summit
Buzz in the Chat: The Low-Carb Plaque Wars • Hospital Privileges
Evidence-based Longevity: ApoB vs. Plaque in LMHR • Blood-based biomarkers for Alzheimer’s • CT scans and cancer risk
Business of Longevity: Lifeforce, Seveno Capital, The Estate, Neko Health, Viome & more strategic moves shaping the space.
The Community Wire: Dr. Omar Saleem
The Calendar: Cannes Summit • DC • Berlin • Portugal
Happy Sunday!!!!
Should We Be Testing Teenagers for Longevity?
This week in the chat, a physician asked:
“Healthy tween/teen, wants baseline labs for hormonal, longevity and overall health. What would all be on your list?”
Some docs recommended core markers like lipids, Lp(a), ApoB, homocysteine, uric acid, vitamin D, and CBC. One added fasting insulin, C-peptide, leptin, adiponectin, resistin, and even DEXA when relevant.
Some advised caution. Others called it smart prevention — especially when subtle symptoms or family history are present.
The question sparked thoughtful clinical insights — and a bigger conversation around the future of prevention:
When does curiosity become pressure? And how do we guide wisely without overstepping?
✅ 5 Reasons You Should Test
Family history matters: early cardiovascular or cancer makes a strong case for early screening.
Early signs, often overlooked: fatigue, mood changes, weight shifts, or period irregularities may signal deeper issues.
Common Deficiencies Go Undetected
Low iron, D, B12, zinc, and omega-3s are frequently missed in “healthy” kids.Mental health has a metabolic link: hormonal and insulin dysregulation can mimic or magnify anxiety and depression.
Good data builds good habits: testing can foster body literacy and long-term health confidence when done thoughtfully.
⚠️ 5 Reasons You Shouldn’t (Yet)
No strong clinical reason: if a teen is thriving, testing might create stress without adding value.
Testing can create obsession: especially in achievement-driven families, it can feed anxiety and fixation.
Adult ranges aren’t always relevant: most labs aren’t calibrated for teens, making interpretation tricky.
Risk of over-medicalizing normal: adolescence is dynamic, not every deviation requires intervention.
Data ≠ wisdom without context: results must be interpreted with clinical expertise, not Google searches.
Dr. David Luu’s Note
Testing should never be done in isolation.
It should be:
Doctor-driven
Based on clinical judgment
Paired with clear education and consent: from both the teen and the parents
Focused on outcomes, not just numbers
Integrated with lifestyle education, mental health, sleep, nutrition, and movement
Used to assess the whole human, not just the lab work
As more companies target Gen Z and tech makes lab data easier to access, interpret, and personalize, we’re entering a new era of proactive health.
And while caution around over-testing is important, it shouldn’t overshadow the daily, unspoken health risks our teens face: social media, ultra-processed food, alcohol, sleep loss, drug exposure.
We need to guide the next generation with context, consent, compassion - and real science.
Longevity medicine starts early — but it should never start without trust.
Let’s lead the next generation with wisdom.
Speaker Spotlight: Dr. Eric Verdin Joins Cannes Longevity Summit
We’re honored to welcome Dr. Eric Verdin, one of the most influential pioneers in longevity science, to the stage at the Cannes Longevity Summit this June.
Dr. Verdin is the President and CEO of the Buck Institute for Research on Aging, the world’s first independent biomedical research institute focused solely on aging and age-related disease.
Dr. Verdin’s research explores how metabolism, diet, and small molecules regulate HDACs and sirtuins: pathways central to aging and diseases such as Alzheimer’s. He has authored over 270 scientific publications, holds 18+ patents, and is recognized among the top 1% of highly cited scientists globally.
Having Dr. Verdin with us in Cannes is more than an honor - it's a sign that longevity medicine is entering its next chapter, where research meets reality.
We can’t wait for you to learn directly from him.
Join us in Cannes for the Longevity Docs Summit - June 25-26, 2025
The Return of the Low-Carb Plaque Wars
A new LMHR (Lean Mass Hyper-Responder) study reignited debate around ApoB, keto, and plaque progression. The study claimed that even metabolically healthy individuals on low-carb diets could show rapid plaque buildup but not everyone agreed.
“This study had a lot of problems. It’s embarrassing it got published.” - Dr NP
“Nutrition is a team sport. Tribalism is killing nuance.”- Dr. AV
“Even Ethan Weiss, who advised Virta, was highly critical.” - Dr. SI
Debate:
Are we seeing real risk - or flawed science amplified by social media echo chambers? Is ApoB always causal? Or context-dependent?
Takeaway:
There’s no one-size-fits-all diet. ApoB matters, but so does context, plaque burden, and personalized intervention. Longevity medicine must stay science-led, not tribe-led.
Hospital privileges: Are you a “low volume provider”?
Dr. RP raised alarm about being flagged as a “low volume provider” - a term hospitals are now using to revoke admitting privileges from physicians with fewer than 50 annual admissions, even if they manage high-acuity patients at home.
“I visit, kick the tires, and remind development that I’m watching... and influence donations.” - Dr. SM
“It’s a squeeze-out. This is how they centralize control.” - Dr. RG
Debate:
Should preventive, concierge-style care disqualify doctors from hospital privileges? Are outpatient-focused MDs being sidelined for financial efficiency?
Takeaway:
The shift to hospitalist-run systems is accelerating. If this trend continues, even top private physicians may lose inpatient access: unless we redefine what “value” looks like in modern care.
Private Club
Member Spotlight
Meet the Longevity Doctors Club members: physicians entrepreneurs building the future of longevity medicine one practice (or more) at the time.
Omar Saleem, MD
Foot & Ankle Surgeon | Founder Precision Orthopedics – Long Island, NY
Dr. Omar Saleem grew up in a family of physicians, so choosing a path of service through medicine came naturally. Today, he leads Precision Orthopedics, a boutique independent clinic delivering high-quality, personalized orthopedic care on Long Island.
Fellowship-trained in foot and ankle surgery, Dr. Saleem treats fractures, tendon injuries, and performs complex reconstructions (including total ankle replacements) with empathy and precision. His team offers a one-stop experience with on-site X-ray, MRI, and physical therapy for fast, seamless care.
Now, Dr. Saleem is also integrating longevity strategies to go beyond recovery: helping patients not just heal, but optimize function, performance, and long-term mobility. His mission: restore movement, confidence, and quality of life.
Join the Longevity Docs Club
If you’re a physician starting or scaling your longevity practice highly vetted Longevity Docs Club is for you.
Join a community of like-minded physicians and gain access to resources on marketing, finance, strategy, and technology to support your independent practice
Applications now open for MD, DO, or MBBS - Limited memberships
Plaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial
This study followed 100 lean, metabolically healthy individuals on a ketogenic diet over one year. Despite elevated LDL-C and ApoB levels, there was no significant association with coronary plaque progression. Instead, baseline plaque burden was the primary predictor of progression, suggesting that existing plaque is a more critical factor than lipid levels in this context.
JACC: Advances (March 2025) - Shared by Dr. Mark Gordon
Advancements in Blood-Based Biomarkers for Alzheimer's Disease
This review discusses the progress in developing blood-based biomarkers (BBMs) for Alzheimer's disease, highlighting their potential for early detection and monitoring. The article emphasizes the need for standardization and validation of BBMs to ensure their effectiveness in clinical practice.
Nature Reviews Neurology (June 2024 - Shared by Dr. Catherine Johnso
Is Low-Dose Radiation From CT Scans a Cancer Risk?
This paper estimates over 100,000 cancers per year may be linked to CT scan radiation exposure. Community debate followed, with some docs questioning model assumptions and real-world relevance.
JAMA Int. Med (2025) - Shared by Dr. Alan Katz
PODCASTS
Matt Kaeberlein joins Bryan Kennedy and Dr. Markus Ranney on the Otherside Podcast
Lipids, Hormones & HRT – Dr. Thomas Dayspring on Dr. Campanile’s The Rest is Health
MEDIA
How AI is decoding multi-omics data to boost health and longevity in Saudi Arabia
Skin Longevity: Staying beautiful and comfortable in one’s skin despite age
If TechCrunch and Longevity had a baby… this would be it.
We track the week’s most strategic moves in innovation, funding, product launches, and talent shifts. This is not just to report them, but to help doctors stay informed, ahead, and equipped to adapt as the field evolves.
Because the future of longevity medicine is being built in real time and you deserve a front-row seat.
Lifeforce Launches Brain Protection Program
The Tony Robbins–backed platform introduces a cognitive health protocol targeting memory, focus, and long-term brain function. More here
Why it matters: Brain health is becoming central to longevity strategies.
Takeaway: Expect more precision health platforms to go deep on brainspan.
Trend watch: Neuro-longevity is emerging as a standalone category.
Seveno Capital Raises $70M Longevity Fund
Entrepreneur Allen Law launches a $70M fund with a first investment in A Cabin Company’s wellness retreats in Japan. Read more
Why it matters: Longevity is now a distinct thesis for venture capital.
Takeaway: Longevity-focused infrastructure is becoming investable.
Trend watch: Hospitality + longevity is heating up fast.
The Estate Names Chief Longevity Officer
The luxury hotel brand by Sam Nazarian and Tony Robbins names Kenneth Ryan as its first CLO to design healthspan-focused guest experiences. Visit
Why it matters: High-end hospitality is embedding longevity into its core offering.
Takeaway: “Longevity hospitality” is the next luxury status symbol.
Trend watch: Healthspan services will reshape travel and recovery.
The £2B Round Longevity Village Approved
A Foster + Partners–designed wellness district in London gets approval for clinics, research hubs, and wellness residences. Read more
Why it matters: Longevity is shaping the blueprint of future cities.
Takeaway: Real estate is being reimagined around healthspan optimization.
Trend watch: Expect more zoning + investment for health-centric communities.
M42 Invests in Juvenescence
The UAE-based health AI firm enters the longevity space with a strategic stake in Juvenescence. More here
Why it matters: Global players are betting big on aging biotech.
Takeaway: MENA is fast becoming a new capital hub for longevity.
Trend watch: AI + longevity partnerships are picking up momentum.
Viome Unveils Full Body Intelligence™
Viome releases its most comprehensive AI-powered test to date, integrating gene expression, microbiome, and aging markers. More here
Why it matters: Multi-omics is becoming standard in personalized medicine.
Takeaway: Testing companies are evolving into health platforms.
Trend watch: Expect biomarker testing to go mainstream.
Neko Health Expands in Europe
Spotify’s Daniel Ek opens the largest Neko Health clinic, offering 10-minute AI-powered full-body scans. Explore
Why it matters: Scalable diagnostics are unlocking preventive care at population scale.
Takeaway: Consumer-driven longevity care is accelerating across Europe.
Trend watch: Preventive health clinics will soon rival urgent care chains.
Skin Analytics Raises €17M
The UK startup raises €17M to expand its AI skin cancer detection platform used across NHS sites. Explore
Why it matters: AI enables earlier, cheaper, and more scalable diagnostics.
Takeaway: Skin is becoming the new biomarker frontier.
Trend watch: Dermatology is entering the longevity tech stack.
Longevity Docs Summit Cannes
This is not just another medical conference, this is the future of cutting-edge longevity medicine.
Join the world’s most visionary longevity physicians, scientists, and innovators for two days of breakthroughs, discoveries, and high-level networking under the French Riviera sun.
Summit. Awards & Black tie Gala. Expo.
📅 Date: June 25-26, 2025
📍 Location: Palace of Festival, Cannes - France
🎟️ Registrations are now open: and spots are limited.
👉 Apply now before it sells out. The New Gods of Medicine will be in Cannes. Will you?
Hormones Mastermind Replay
For the first time, get full online access to the entire event:
✔ 10 expert-led modules
✔ Real-world protocols and case studies
✔ On-demand viewing, anytime, anywhere
No fluff, no travel: just pure, actionable hormone and longevity education.
Replay Pass: $295
Longevity Conferences Calendar
A4LI DC Summit: Washington DC - April 28-30
The Longevity Med Summit - Lisbon, May 6-8
Life Summit - Berlin, May 27-28
Dublin Longevity Summit: Dublin, July 2–4
ARDD: Coppenhagen, August 25-29
Why every doctor should be a longevity doctor.
The Movement
Longevity Docs is the world’s leading collective of physicians advancing longevity medicine through education, clinical research, advisory, and exclusive experiences. With over 400 members in 50+ countries, we’re building the global infrastructure for evidence-based, personalized longevity care.
Why “Longevity Docs”?
Because we believe longevity is not a specialty — it’s a human right.
The future of medicine is proactive, not reactive. It's interdisciplinary, not isolated. It’s collaborative, data-driven, and deeply human. And it starts with us — the physicians who dare to redefine what care looks like across the decades of a patient’s life.
“Longevity Docs” isn’t just a name. It’s a statement of purpose.
Our Ecosystem
Physician Network
A trusted global collective of longevity-focused doctors exchanging protocols, referrals, and real-world clinical outcomes.Education & Certification
Earn your Certified Longevity Physician™ designation through our advanced curriculum, live masterclasses, and continuous learning tracks.Decentralized Research
Lead or participate in multicenter clinical trials and patient registries, accelerating evidence generation for healthspan optimization.Strategic Advisory
We partner with vetted longevity companies, life-science, tech, and clinics to help them grow.Global Events & Experiences
Access exclusive gatherings like the NYC Mastermind and the Cannes Longevity Summit & Awards
Who It’s For
Doctors → Join the club, get certified, grow your practice
Health Systems → Implement clinical longevity programs
Brands & Startups → Validate products, find advisors, run trials
Investors → Gain early access to insights, doctors, and deal flow
Subscribe to the Longevity Docs Newsletter
Stay connected with the backstage of the Longevity Docs community, a network of over 400 physicians spanning 50 countries, united in our mission to democratize longevity medicine. Explore the latest in evidence-based longevity care, gain exclusive access to physician insights, and join us in shaping the future of this transformative field.
Newsletter Disclaimer:
The content shared in this newsletter, including the "Buzz in the Chat" section, is for educational purposes only. It is derived from peer-to-peer conversations among physicians within the Longevity Docs community and is intended to inform and engage our network of doctors.
Please note that these discussions do not reflect the official position of Longevity Docs and are not to be interpreted as medical advice or recommendations. The insights and opinions shared are those of individual physicians and are provided as part of our mission to foster collaborative learning and dialogue among healthcare professionals.
We encourage all readers to consult qualified healthcare professionals for personalized medical advice and to evaluate any medical information in the context of their clinical expertise and patient needs.